Group leader: Sven Enerbäck
Members of the group: Zahra Arani, Michal Bell, Anna Cederberg, Mats Grände, Mikael Heglind, Daniel Nilsson, Sandra Rodrigo-Blomqvist, Gunilla Petersson, Rickard Westergren and Hilmar Vidarsson

Sven Enerbäck's publications

Di Gregorio GB, Westergren R, Enerbäck S, Lu T, Kern PA.
Expression of FOXC2 in Adipose and Muscle and its Association with Whole-Body Insulin Sensitivity.
Am J Physiol Endocrinol Metab. 2004 Jun 15 [Epub ahead of print]

Blomqvist SR, Vidarsson H, Fitzgerald S, Johansson BR, Ollerstam A, Brown R, Persson AE, Bergström G G, Enerbäck S.
Distal renal tubular acidosis in mice that lack the forkhead transcription factor Foxi1.
J Clin Invest. 2004 Jun;113(11):1560-70.

Hansen JB, Jorgensen C, Petersen RK, Hallenborg P, De Matteis R, Boye HA, Petrovic N, Enerbäck S, Nedergaard J, Cinti S, te Riele H, Kristiansen K. Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.
Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4112-7.

Harndahl L, Wierup N, Enerbäck S, Mulder H, Manganiello VC, Sundler F, Degerman E, Ahren B, Holst LS.
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology. J Biol Chem. 2004 Apr 9;279(15):15214-22.

Yang X, Enerbäck S, Smith U.
Reduced expression of FOXC2 and brown adipogenic genes in human subjects with insulin resistance.
Obes Res. 2003 Oct;11(10):1182-91.

Yanagisawa K, Hingstrup Larsen L, Andersen G, Drivsholm T, Cederberg A, Westergren R, Borch-Johnsen K, Pedersen O, Enerbäck S, Hansen T.
The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects. Diabetologia. 2003 Nov;46(11):1576-80.

Winzell MS, Svensson H, Enerbäck S, Ravnskjaer K, Mandrup S, Esser V, Arner P, Alves-Guerra MC, Miroux B, Sundler F, Ahren B, Holm C.
Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase.
Diabetes. 2003 Aug;52(8):2057-65.

Johansson CC, Dahle MK, Blomqvist SR, Gronning LM, Aandahl EM, Enerbäck S, Tasken K.
A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha.
J Biol Chem. 2003 May 9;278(19):17573-9.

Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerbäck S.          
Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice.
Development. 2003 May;130(9):2013-25.

Cederberg A, Enerbäck S.         
Insulin resistance and type 2 diabetes--an adipocentric view.
Curr Mol Med. 2003 Mar;3(2):107-25. Review.

Ridderstrale M, Carlsson E, Klannemark M, Cederberg A, Kosters C, Tornqvist H, Storgaard H, Vaag A, Enerbäck S, Groop L.           
FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance.
Diabetes. 2002 Dec;51(12):3554-60.

Gronning LM, Cederberg A, Miura N, Enerbäck S, Tasken K.        
Insulin and TNF alpha induce expression of the forkhead transcription factor gene Foxc2 in 3T3-L1 adipocytes via PI3K and ERK 1/2-dependent pathways.
Mol Endocrinol. 2002 Apr;16(4):873-83.

Cederberg A, Gronning LM, Ahren B, Tasken K, Carlsson P, Enerbäck S.
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance.
Cell 2001 Sep 7;106(5):563-73

Cederberg A, Hulander M, Carlsson P, Enerbäck S
The kidney-expressed winged helix transcription factor FREAC-4 is regulated by ets-1. A possible role in kidney development.
J Biol Chem 1999 Jan 1;274(1):165-9

Hulander M, Wurst W, Carlsson P, Enerbäck S
The winged helix transcription factor Fkh10 is required for normal development of the inner ear.
Nat Genet 1998 Dec;20(4):374-6

Ernstsson S, Betz R, Lagercrantz S, Larsson C, Ericksson S, Cederberg A, Carlsson P, Enerbäck S
Cloning and Characterization of freac-9 (FKHL17), a Novel Kidney-Expressed Human Forkhead Gene That Maps to Chromosome 1p32-p34.
Genomics 1997 Nov 15;46(1):78-85

Cederberg A, Betz R, Lagercrantz S, Larsson C, Hulander M, Carlsson P, Enerbäck S
Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene.
Genomics 1997 Sep 15;44(3):344-6

Ernstsson S, Pierrou S, Hulander M, Cederberg A, Hellqvist M, Carlsson P, Enerbäck S
Characterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53.
J Biol Chem 1996 Aug 30;271(35):21094-9